🚨New Poster Drop — Featured at ASGCT 2026
dsRNA contamination in mRNA therapeutics isn't just a quality issue — it's a translation killer and an immune system alarm.
Our latest research poster, "Enzymatic Elimination of dsRNA Byproducts Enhances Translation and Reduces Innate Immune Activation of mRNA," presented at ASGCT 2026, shows just how much it matters — and what you can do about it.
Key findings:
✅ Up to 99.9% reduction in dsRNA using our Min-Immune™ Gold dsRNA Removal Kit
✅ Up to 55× improvement in luciferase activity for canonical UTP mRNA
✅ Average 81–86% suppression of primary dsRNA sensors (RIG-I, TLR3, MDA5, OAS1)
✅ Enzymatic dsRNA removal is additive to nucleotide substitution
• Even N1meΨ mRNA gains ~1.8× more immune suppression when treated
✅ Works across HEK293, A549, and immune-sensitive JAWSII cell lines
Whether you're developing engineered cell therapies, cell reprogramming workflows, or next-gen mRNA therapeutics — dsRNA removal is no longer optional.
dsRNA contamination in mRNA therapeutics isn't just a quality issue — it's a translation killer and an immune system alarm.
Our latest research poster, "Enzymatic Elimination of dsRNA Byproducts Enhances Translation and Reduces Innate Immune Activation of mRNA," presented at ASGCT 2026, shows just how much it matters — and what you can do about it.
Key findings:
✅ Up to 99.9% reduction in dsRNA using our Min-Immune™ Gold dsRNA Removal Kit
✅ Up to 55× improvement in luciferase activity for canonical UTP mRNA
✅ Average 81–86% suppression of primary dsRNA sensors (RIG-I, TLR3, MDA5, OAS1)
✅ Enzymatic dsRNA removal is additive to nucleotide substitution
• Even N1meΨ mRNA gains ~1.8× more immune suppression when treated
✅ Works across HEK293, A549, and immune-sensitive JAWSII cell lines
Whether you're developing engineered cell therapies, cell reprogramming workflows, or next-gen mRNA therapeutics — dsRNA removal is no longer optional.
📥 Download the full poster here:
Ready to eliminate dsRNA from your workflow? Explore the full INCOGNITOâ„¢ + Min-Immuneâ„¢ Gold dual workflow at Immunogenicity Reduction
Copyright © 2026 CELLSCRIPT™
All rights reserved.
All rights reserved.
Mailing Address
726 Post Road
Madison, WI 53713
USA
726 Post Road
Madison, WI 53713
USA